We use the tools of synthetic biology, computational biology, and microfluidic devices to advance our understanding of biological systems, especially genetic networks.
"Synthetic Biology, Real Mathematics," an article in SIAM News, discusses the need for mathematical modeling in synthetic biology and highlights our recent work on temperature compensation.
An article in The Scientist on mind-controlled gene regulation quotes Dr. Bennett.
David's new paper on chimeric protein-mediated logic gating made the cover of ACS Synthetic Biology.
Jae's new paper on improving stochastic simulations of gene networks appeared in Biophysical Journal.
Read the Rice press release on David's new research here.
David's commentary on new biotechnologies using split T7 RNAP was published in Molecular Systems Biology.
Shis DL, Hussain F, Meinhardt S, Swint-Kruse L & Bennett MR, “Modular, multi-input transcriptional logic gating with orthogonal LacI/GalR family chimeras,” ACS Synth. Biol. 3, 645-651 (2014). [PDF]
Kim JK, Josic K & Bennett MR, “The validity of quasi-steady-state approximations in discrete stochastic simulations,” Biophys. J. 107, 783-793 (2014). [PDF]
Shis DL & Bennett MR, “The many facets of T7 RNA polymerase,” Mol. Syst. Biol. 10, 745 (2014). [PDF]
Kim JK, Kilpatrick ZP, Bennett MR & Josic K, "Molecular mechanisms that regulate the coupled period of the mammalian circadian clock." Biophys. J. 106, 2071-2081 (2014). [PDF]
Hussain F, Gupta C, Hirning AJ, Ott WR, Matthews KS, Josic K & Bennett MR, “Engineered temperature compensation in a synthetic genetic clock.” Proc. Natl. Acad. Sci. USA 111, 972-977 (2014). [PDF]